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Ramipril – njursvikt – ej diabetes
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Intensiv terapi – diabetes
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Äldre med systolisk hypertoni – diabetes resp icke diabetes
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HOPE The Heart Outcomes Prevention Evaluation Study Investigators. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on death from cardiovascular causes, myocardial infarction, and stroke in high-risk patients. N Engl J Med 2000 Jan 20;342:145-53.
RENAAL Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Eng J Med 2001;12:861-869.
IDNT Renoprotective effect of the angiotensin-receptoragonist irbesartan with nephropathy due to type II diabetes. N Engl J Med 2001;345:851- 60.
IRMA-2 The effect of irbesartan on the development of diabetic nephropathy in patients with type II diabetes. N Eng J Med 2001;345:870-8.
LIFE Dahlöf B, Devereux RB, Kjeldsen SE Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002;359:995–1003.
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ANBP2 A comparison of Outcomes with Angiotensin-converting-Enzyme Inhibitors and Diuretics for Hypertension in the Elderly. The Second Australian National Blood Pressure Study Group (ANBP2). N Engl J Med 2003;348:583-592.
SCOPE The study on cognition and prognosis (SCOPE): principal results of a randomized double-blind intervention trial. Journal of Hypertension 2003,21:875-886.
SBU rapport nr 170/1, 2004: Måttligt förhöjt blodtryck www.sbu.se
Metaanalys Effects of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists on mortality and renal outcomes in diabetic nephropathy: systematic review. BMJ 2004;329:828831.
VALUE Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004;363:2022-2031.
Lindholm LH, Carlberg B, Samuelsson O. Should ß blockers remain first choice in the treatment of primary hypertension? A meta-analysis. Lancet 2005;366:1545-53.
Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet 2008;366:895-906.
ADVANCE Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes (the ADVANCE trial): a randomised controlled trial. Lancet 2007;370:829-40.
ONTARGET Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events.The ONTARGET Investigators. N Engl J Med 2008;358:1547-59.
TRANSCEND Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. The TRANSCEND Investigators. Lancet 2008;372:1174-83.
HYVET Beckett NS et al. The HYVET Study Group. Treatment of Hypertension in Patients 80 Years of Age or Older. N Engl J Med 2008
ACCOMPLISH Jamerson K,Weber MA, Bakris GL, et al. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. New Engl J Med 2008;359:2417-28.
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HOPE-3 Yusuf S, et al. Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease. The New England Journal of Medicine. 2016. 374(21):2032-2343
SCORE2 working group and ESC Cardiovascular risk collaboration. SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe. Eur Heart J. 2021;42(25):2439-54.
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Hur mycket salt äter vi i Sverige? En uppskattning av befolkningens saltintag från befintliga data (livsmedelsverket.se)